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Genomics, Signaling, and Treatment of Waldenstrom's MacroglobulinemiaWaldenström’s macroglobulinemia (WM) is a distinct B-cell malignancythat results from the accumulation, predominantly in the bone marrow, of clonally related B type lymphocytes, lymphoplasmacytic cells and plasma cells which secrete a monoclonal IgM protein.1 This condition is considered to correspond to the lymphoplasmacytic lymphoma (LPL) as defined by the World Health Organization classification system.2 Most cases of LPL are WM, with less than 5% of cases made up of IgA, IgG and non-secreting LPL ...

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A 70-year-old New Brunwick man to walk 300 kilometres for rare cancer awareness

A 70-year-old New Brunwick man to walk 300 kilometres for rare cancer awareness

A Rothesay man fighting a rare cancer is stepping up to raise awareness about the disease. And as Travis Fortnum reports, he’s planning a month-long walk to do it.

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2021 IWMF Global Educational Webinar with Dr. Stephen Ansell & Dr. Jorge Castillo

2021 IWMF Global Educational Webinar with Dr. Stephen Ansell & Dr. Jorge Castillo

Our IWMF experts will share an update on the status of existing COVID-19 vaccines and others in development. This interactive LIVE question and answer session will explain side effects and recommendations for WM patients.

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Clinical Trials Are Moving Out of the Lab and Into Peopleʼs Homes

Clinical Trials Are Moving Out of the Lab and Into Peopleʼs Homes

After the pandemic forced thousands of trials to shut down, researchers found clever ways to conduct human studies remotely — while reaching more people, quickly and cheaply.

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Current and Future Treatments for Waldenstrom Macroglobulinemia

Current and Future Treatments for Waldenstrom Macroglobulinemia

What are the treatments for Waldenstrom macroglobulinemia and what's in the pipeline? Can Waldenstrom patients plan for a higher quality of life? Dr. Jorge Castillo, Clinical Director, Bing Center for Waldenstrom Macroglobulinemia, Dana Farber Cancer Institute, presents an overview of his presentation at the 2020 IWMF with Patient Power co-founder Andrew Schorr.

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Progress in the Treatment of Waldenstrom’s Macroglobulinemia (Webcast)

Progress in the Treatment of Waldenstrom’s Macroglobulinemia (Webcast)

Workshop Date and Time: Wednesday, April 21, 2021, 12:30 – 1:30 pm, Eastern Time. Registrants can listen in live over the phone or online as a webcast.

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Current and novel BTK inhibitors in Waldenström’s macroglobulinemia

Current and novel BTK inhibitors in Waldenström’s macroglobulinemia

Ioannis Ntanasis-Stathopoulos, Maria Gavriatopoulou, Despina Fotiou and Meletios A. Dimopoulos present a summary of trial findings and details regarding various BTK inhibitors, including ibrutinib, zanubrutinib, acalabrutinib, tirabrutinib, LOXO-305, etc.

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BeiGene (BGNE) Announces U.S. FDA Acceptance of Supplemental New Drug Application for BRUKINSA in Waldenstrom's Macroglobulinemia

BeiGene (BGNE) Announces U.S. FDA Acceptance of Supplemental New Drug Application for BRUKINSA in Waldenstrom's Macroglobulinemia

BeiGene, Ltd. (NASDAQ: BGNE; HKEX: 06160), a commercial-stage biotechnology company focused on developing and commercializing innovative medicines worldwide, today announced that the U.S. Food and Drug Administration (FDA) has accepted a supplemental new drug application (sNDA) for BRUKINSA® (zanubrutinib) for the treatment of adult patients with Waldenström’s Macroglobulinemia (WM). The Prescription Drug User Fee Act (PDUFA) target action date is October 18, 2021.

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Podcast with Dr. Jorge Castillo: MGUS, Myeloma, WM AND Immunology, Oh My!

Podcast with Dr. Jorge Castillo: MGUS, Myeloma, WM AND Immunology, Oh My!

December 21, 2020: Dr. Jorge Castillo walks us through immunology basics, teaches us the limitations of the SPEP, plus some additional tests that complement it (think Immunofixation), shares his clinical gestalt about when to suspect MGUS, Myeloma, Waldenstrom’s, and Amyloidosis–and finally, how to talk to patients about them.

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International Myeloma Society Recommendations for Covid-19 vaccinations in patients with MM and related conditions

International Myeloma Society Recommendations for Covid-19 vaccinations in patients with MM and related conditions

Dear IMS Member: We hope you are well during these difficult times. As a response to the current pandemic, the International Myeloma Society has developed the following Recommendations for anti-Covid-19 vaccination in patients with multiple myeloma (MM) and related conditions, AL amyloidosis and other monoclonal gammopathies of clinical significance.

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Cancer and the COVID-19 Vaccine

Cancer and the COVID-19 Vaccine

On January 27, Dana Farber held a webinar to review the information regarding COVID-19 vaccinations for patients. Catherine Flynn (from the Bing Center Clinic) shares the following highlights from the webinar.  Note, the entire webinar was recorded and posted to Facebook, using the following link:

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